The interesting work of John Ioannidis

Interesting article from the Atlantic on the work of meta-researcher John Ioannidis. It's of course not so surprising that medical research should fare so poorly in his studies. It would be interesting to see how other fields fared, though it is hard to see how other fields would be exempt from the influences affecting medicine and physiology. What's disturbing though is the trust we as a society put in medical research, not only emotionally but also economically.

(Graph courtesy of AAAS.) This is a frightening graph in many ways. We are on the cusp of a full-fledged energy crisis, yet the amount invested in energy research is a pittance compared to the money we're throwing away at medicine. As Ioannidis points out, the more money we throw at the field, the more phony results are likely to turn up. Still, it would make me a lot more comfortable to know that the field is given resources proportionate to its importance.

The other interesting element this article presents is whether the general trust the public has in science should be allowed to tarnish due to public exposure to Ioannidis's work. Doctors are held in special esteem by the general public, and for large swaths of the practice to be exposed as little more than fraud doesn't do much for the public acceptance of science (not to mention how it might poison the health-care debate in the US). Truly important issues of climate change, energy policy, stem-cell research, high-energy particle physics experiments, and science education can all be questioned by a science-questioning public (just look at the comments section of this NYT opinion column on climate change), but the public needs to maintain an open and tolerant mind, subject to change. I have no doubt that there is lots of lousy climate science out there, but the bulk and breadth of the total research combines to constitute fairly robust knowledge.

But the original article is of particular interest when one considers that the pharmaceuticals we're being fed unnecessarily end up right in the ecosystem. If we can trust her research, of course.